Sher was born inLos Angeles, Californiaon December 26, 1991 to a Jewish family. She was raised by her mother, a single school teacher. She has both an older and a younger brother and three dogs.She began her acting career at age eight by participating in school plays, local theater productions and singing in her elementary school chorus.Her interest in acting was ignited after a recording of one of her school performances appeared onThe Tonight Show with Jay Leno.

Throughout her years as an actress, Sher has played a number of roles in television series, but many of these were short lived, as the series were either canceled or her character was eliminated. It was not until she landed a role as Sue Heck on the television seriesThe Middlethat she gained a starring and more permanent role. Since 2009, Sher has starred in the ABC comedy seriesThe Middleas Sue Heck, a quirky but optimistic teenager. In 2013, she won theCritics' Choice Television Award for Best Comedy Supporting Actressfor her role inThe Middle.In 2006, she played the role of Gretchen, a middle school love interest for one of the main characters, Alexander Gould, in the comedy-drama seriesWeeds. Later that same year, she landed the regular role of Carrie Fenton onSons & Daughters, which was canceled 11 episodes into its first season.In 2007, Sher played a student attending Harbor High in the final season of the seriesThe O.C..She also appeared in the 2001 short film "Stuck" and ads forCapital OneandFruity Pebbles.

2001年9月，首次参演美国电影短片《Stuck》饰演Caterpillar Girl。

左右不逢源

2006年3月，首次参演美国电视剧《Sons & Daughters》饰演Carrie Fenton。

2006年8月，参演美国电视剧《单身毒妈第二季》饰演Gretchen。

2009年9月，参演美国家庭情景喜剧《左右不逢源》饰演休·赫克。

2013年，自编自导短片喜剧《The Suitcase》并担任製片人。

2015年，担任喜剧片《ImagiGARY》并担任执行製片人。

2016年，参加电视喜剧节目《Sing It!》。

Mother is a teacher

Has two siblings

Has 3 dogs

Enjoys singing and taking theater

Has previously done various sketches onThe Tonight Show with Jay Leno(1992).

星蝶公主（2015）Star Butterfly/Starn（配音）

Stalker Chronicles（2010）Jenny（配音）